AGENDA

The program of the International Magnetic Resonance Workshop: “MRS 2022: Overcoming the Barriers to Clinical Use” is spread over 3 days and contains 9 scientific sessions.
The sessions cover educational invited topics from the basics to the recent advancements in the field and proffered oral presentations based on submitted abstracts by PhD students or senior scientists describing the latest advancements in the field.
In addition, onsite poster sessions, lunches, breaks, a panel discussion and a dinner are organized to facilitate and provide ample opportunity for students to meet and share their exciting work with their peers and MRS experts in-person. Given the lack of in-person events over the last two years due to COVID-19, we feel it is of high value and importance for researchers that just entered the field to have informal discussions with each other and the more senior scientists.

Presentations and recordings are now available!

Day 1: Monday 22 of August

08:30-10:00   Onsite registration and posters 

10:00-10:20   Welcome & Introduction

  • Cristina Cudalbu, CIBM MRI EPFL, Lausanne, Switzerland

10:20-12:20   Session 1 – MRS: back to basics

Moderators:

  • François Lazeyras, CIBM MRI HUG-UNIGE Clinical MR Imaging Section
  • Gianna Nossa, Dydak Lab/ Health Science, Purdue University, U.S.A.

10:20-10:45   Basics of MRS: SVS and MRSI

  • Georg Oeltzschner, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A. & F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, U.S.A.

10:45-11:10   The neurochemical profile

  • Steve Williams, Imaging Science, University of Manchester, UK

11:10-11:35   Spectral editing

  • Kimberley Chan, Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

11:35-11:50   MRSHub – What’s new?

  • Candace Fleischer, Emory University, Atlanta, U.S.A.

11:50-12:20   Proffered presentations based on submitted abstracts 

  • 11:50 – 12:05   Adaptive Magnetic Resonance, Assaf Tal et al.

  • 12:05- 12:20   Does visual stimulation always lead to an increase in glutamate concentration?, Katarzyna Wasilewska et al.

12:20-14:00   Lunch onsite: Meet the experts! break the ice

Moderators:

  • Dunja Simicic, CIBM MRI EPFL, Lausanne, Switzerland
  • Jessie Mosso, CIBM MRI EPFL, Lausanne, Switzerland
  • Brayan Alves, CIBM MRI EPFL, Lausanne, Switzerland

  • Rudy Rizzo, University of Bern, CH

  • Kay Chioma Igwe, Columbia University, USA

  • Dario Goranovic, Medical University of Vienna, Austria

  • Gianna Nossa, Dydak Lab/ Health Science, Purdue University, USA

  • Ryan Armbuster (online), Center for Advanced Metabolic Imaging in Precision Medicine, University of Pennsylvania, USA

  • Kelley M. Swanberg (online), Columbia University, USA

14:00-15:30   Session 2: Artifacts and Correction (B0, B1, motion, ..)

Moderators:

  • Ivan Tkac, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, U.S.A.
  • Ipek Ozdemir, School of Medicine/Neuroradiology, Johns Hopkins University, Baltimore, USA

14:00-14:25   Artifacts and Correction in MRS and MRSI

  • Michal Povazan, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Amager and Hvidovre, Hvidovre, Denmark

14:25-14:50   Quality control & preprocessing

  • Nuno Barros, Icometrix, Leuven, Belgium

14:50-15:35   Proffered presentations based on submitted abstracts 

  • 14:50-15:05   Fast prospective motion correction for spectroscopic acquisitions, Isaac Adanyeguh et al.
  • 15:05-15:20  Deep Learning Pipeline for Quality Filtering of MRSI Spectra, Mladen Rakic et al.
  • 15:20- 15:35   Effect of circadian rhythm on brain NAD: a magnetic resonance spectroscopy study at 7 T, Zhiwei Huang et al.

15:35-16:10   Break: Meet the experts! break the ice

Moderators:

  • Dunja Simicic, CIBM MRI EPFL, Lausanne, Switzerland
  • Jessie Mosso, CIBM MRI EPFL, Lausanne, Switzerland
  • Brayan Alves, CIBM MRI EPFL, Lausanne, Switzerland

  • Rudy Rizzo, University of Bern, Switzerland

  • Kay Chioma Igwe, Columbia University, U.S.A.

  • Dario Goranovic, Medical University of Vienna, Austria

  • Gianna Nossa, Dydak Lab/ Health Science, Purdue University, U.S.A.

  • Ryan Armbuster (online), Center for Advanced Metabolic Imaging in Precision Medicine, University of Pennsylvania, U.S.A.

  • Kelley M. Swanberg (online), Columbia University, U.S.A.

16:10-18:00   Session 3: Accelerated MRSI and reconstruction

Moderators:

  • Antonia Susnjar, Rispoli Lab/ Biomedical Engineering, Purdue University, West Lafayette, USA
  • Bernhard Strasser, High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria

16:10-16:35   Accelerated MRSI: conventional approaches

  • Ovidiu Andronesi, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.

16:35-17:00   Accelerated MRSI: Advanced techniques

  • Antoine Klauser, CIBM MRI HUG-UNIGE, Geneva, Switzerland

17:00-18:00   Proffered presentations based on submitted abstracts 

  • 17:00-17:15   Outlier Rejection for Fetal and Neonatal Brain MRS, Jack Highton et al.
  • 17:15-17:30   Towards simultaneous concentration and T2 mapping of brain metabolites by multi-echo spectroscopic imaging, R Rizzo et al.
  • 17:30 -17:45   MP-PCA and LR-TGV denoising in 1H-FID-MRSI data at 14.1T: application and validation, Brayan Alves et al.
  • 17:45-18:00   Downfield proton MRSI in the human brain with extended spatial coverage, Ipek Özdemir et al.

Day 2: Tuesday 23 of August

08:30-10:15   Session 4: Spectral Fitting and Quantitation

Moderators:

  • Phil Lee, Department of Radiology, Hoglund Biomedical Imaging Center, University of Kansas Medical Center, Kansas City, Kansas, U.S.A.
  • Rudy Rizzo, University of Bern, Switzerland

08:30-08:55   Metabolite basis set simulations

  • Karl Landheer, Regeneron Pharmaceuticals, Tarrytown, NY, U.S.A.

08:55-09:20   Parametric fitting

  • Anke Henning, Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, U.S.A.

09:20-09:45   Quantification: references, T1, T2 and macromolecules

  • Niklaus Zölch, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland & Institute of Forensic Medicine, Department of Forensic Medicine and Imaging, University of Zurich, Zurich, Switzerland

09:45-10:15   Proffered presentations based on submitted abstracts

  • 09:45-10:00   Investigating Glutamate T2 relaxation time, Polina Emeliyanova et al.
  • 10:00-10:15 Uncertainty Propagation in Absolute Metabolite Quantification for In Vivo Magnetic Resonance Spectroscopy of the Human Brain, Ronald Instrella et al.

10:15-10:45   Break: Meet the experts! break the ice

10:45-12:30   Session 5: Preclinical & Clinical Session

Moderators:

  • Ralf Mekle, Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany
  • Alireza Abaei, Core facility Small Animal Imaging / Medical Faculty, Ulm University, Germany

10:45-11:10   Preclinical MRS

  • Bernard Lanz, CIBM MRI EPFL, Lausanne, Switzerland

11:10-11:35   Translational work bench-bedside

  • Itamar Ronen, The Clinical Imaging Sciences Centre,Brighton and Sussex Medical School, University of Sussex, UK

11:35-12:00   Methods for non-brain translational and clinical MRS

  • Martin Krssak, Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria & High-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria

12:00-12:30   Proffered presentations based on submitted abstracts

  • 12:00-12:15   α-ATP suppression in 31P MR spectroscopy by homonuclear BIRD editing: An approach to quantify NADH and NAD+ at 3T in vivo in skeletal muscle, J. Mevenkamp et al. 

    Watch the recording here MRS 2022 Workshop, Day 2 – YouTube

  • 12:15-12:30   Association of insulin resistance with the accumulation of saturated IMCL, compared with other fat stores, Mueed Azhar et al.

    Watch the recording here MRS 2022 Workshop, Day 2 – YouTube

12:30-14:00   Lunch onsite: Meet the experts! break the ice

14:00-15:40   Session 6: Accuracy and rigor

Moderators:

  • Julien Valette, Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives (UMR 9199), Fontenay-aux-Roses, France
  • Jessie Mosso, CIBM MRI EPFL, Switzerland

14:00-14:25   Validation, reproducibility/repeatability in MRS

  • Gulin Oz, Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, U.S.A.

14:25-14:50   Vendor harmonization in MRS

  • Dinesh Deelchand, Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, U.S.A.

14:50-15:15   Denoising for MRS and MRSI

  • William Clarke, Wellcome Center for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK & MRC Brain Network Dynamics Unit, University of Oxford, Oxford, UK

15:15-15:40   Machine learning for MRS/MRSI

  • Hyeonjin Kim, Department of Medical Sciences, Seoul National University, Seoul, South Korea; Department of Radiology, Seoul National University Hospital, Seoul, South Korea.

15:40-17:00   Break: Meet the experts! break the ice
Traditional Poster Session

Moderators:

  • Jessie Mosso, CIBM MRI EPFL, Lausanne, Switzerland
  • Hélène Lajous, CIBM SP CHUV-UNIL, Lausanne, Switzerland

18:00-19:00   Welcome Cocktail – Olympic Museum
18:30-20:00   Visit Olympic Museum
20:00-23:30   Dinner – Olympic Museum

Day 3: Wednesday 24 of August

08:30-10:15   Session 7: Clinical applications of MRS

Moderators:

  • Peter Barker, Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, U.S.A.
  • Kay Chioma Igwe, Columbia University, U.S.A.

08:30-08:55   Brain MRS in psychiatry

  • Lawrence S Kegeles, New York State Psychiatric Institute (NYSPI), New York, NY, U.S.A.

08:55-09:20   Brain MRS in cancer

  • Otto Rapalino, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.& Harvard Medical School, Boston, Massachusetts, U.S.A.

09:20-09:45   MRS in pediatrics

  • Petra Pouwels, Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, The Netherlands

09:45-10:15   MRS application in liver and muscle

  • Vera Schrauwen-Hinderling, Department of Imaging / Nutrition and Movement Sciences NUTRIM School of Nutrition and Translational Research in Metabolism Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands

10:15-10:45   Break: Meet the experts! break the ice

10:45-12:30   Session 8: Panel Discussions

Moderators:

  • In-Young Choi, Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, U.S.A.
  • Roland Kreis, Magnetic Resonance Methodology group of the University Institute for Diagnostic and Interventional Neuroradiology and the Department of Biomedical Research, University Bern, Bern, Switzerland

10:45-11:25   Consensus papers: from consensus papers to impact – Panel discussion

  • Christoph Juchem, Department of Biomedical Engineering, Columbia University Fu Foundation School of Engineering and Applied Science, New York, New York, U.S.A. & Department of Radiology, Columbia University College of Physicians and Surgeons, New York, New York, U.S.A.
  • Jodi Weinstein, Stony Brook School of Medicine, Stony Brook, NY, U.S.A.

11:25-12:05   Accelerated MRSI: quality control and validation of fast methods – Panel discussion

  • Wolfgang Bogner, High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria
  • Cristina Cudalbu, CIBM MRI EPFL, Lausanne, Switzerland
  • Jannie Wijnen, High Field MR Research, Centre for Image Sciences, University Medical Centre Utrecht, Utrecht, The Netherlands

12:05-12:35   Proffered presentations based on submitted abstracts

  • 12:05-12:20   Accurate prediction of IDH-mutation status of gliomas using SLOW- editing MRSI at 7 Tesla MR, Guodong Weng et al.
  • 12:20-12:35  Probing diffusion of water and metabolites to assess white matter microstructure in Duchenne muscular dystrophy, R. Govaarts et al.

12:35-14:00   Lunch onsite & Posters. Meet the experts! break the ice

14:00-16:00   Session 9: Emerging techniques X-nuclei, high field

Moderators:

  • PG Henry, Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, U.S.A.
  • Dario Goranovic, Medical University of Vienna, Austria.

14:00-14:25   Deuterium MRSI

  • Jeanine Prompers, Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands

14:25-14:50   Hyperpolarized 13C: where are we in the clinic?

  • Christoffer Laustsen, The MR Research Center, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark

14:50-16:05   Proffered presentations based on submitted abstracts 

  • 14:50-15:05   Non-invasive 3D mapping of downstream brain glucose metabolism using 1H MRSI with deuterium labeling at 3T, Fabian Niess et al.
  • 15:05-15:20   Comparing cerebral metabolism of hyperpolarized 13C-glucose and thermally polarized deuterated glucose under different anesthetic conditions, Mor Mishkovsky et al.

   Watch the recording here MRS 2022 Workshop, Day 3 – YouTube

  • 15:20-15:35   Retrospective under-sampled 3D Deuterium Metabolic Imaging (DMI) of the Human Liver with Low-rank and Subspace Modeling at 7T, Kyung Min Nam et al.
  • 15:35-15:50   DMI using different doses of [6,6′-2H2]-glucose for real-time in vivo liver glucose mapping at 7 T, Simone Poli et al.

   Watch the recording here MRS 2022 Workshop, Day 3 – YouTube

  • 15:50-16:05   Anesthetic-related neuroenergetic changes measured with 1H- and 31P-MRS in mouse at 7 Tesla, Antoine Cherix et al.

   Watch the recording here MRS 2022 Workshop, Day 3 – YouTube

16:00-17:00   Closing remarks and Au revoir !

  • Wolfgang Bogner, Medical University Vienna, Austria – chair of the MRS Study Group at ISMRM

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